a toolbox to visualize and analyze DNA methylation data

1999 © Christoph Grunau, Ruben Schattevoy, Niels Mache, André Rosenthal


MethTools is a collection of software tools for the handling and analysis of DNA methylation data generated by the Bisulfite Genomic Sequencing method. A detailed description of the programs has been published in Nucleic Acids Res 2000 Mar 1;28(5):1053-1058. and as pdf-File

If you are familiar with the UNIX system and the programming language PERL you may proceed directly to the download page. Users who wish to have a step-by-step installation instruction, please proceed with "Installation".

In case you experience problems during installation or the use of the programs, please do not hesitate to contact the authors.

If you want access the DNA methylation Database (MethDB) please visit http://www.methdb.net.

Changed 12/03/2007 (bsenf):
- Bug fixed - only select '5mC desity plot as png-image' will break pipeline with error 'Cannot delete FASTA file'.
- New - files will leave on server for only a few days now;

Changed 10/07/2006 (bsenf,grunau):
Version 1.3: Attach all files as single zip file

Changed 04/10/2003 (bsenf):
We provide only GD library that supports PNG files. So it was necessary to change some perl code like:
   old: print im->gif;
   new: print im->png;

Changed 04/12/2003 (bsenf):
Due to fit postscript output to page A4 the scaleing factor was reduced to 90percent.

Software Disclaimer: The software products of the MethTools suite have been tested extensively on our computers. However, it is distributed without warranty of any kind, either expressed or implied. Neither the authors nor the distributors assume any liability for any alleged or actual damages arising from the use of or the inability to use this software.

Leibniz Institute for Age Research - Fritz Lipmann Institute
Genome Analysis
07745 Jena
Fax: +49 - 3641 - 65 62 55